Penguins GM Ray Shero assured reporters on Wednesday that Letang is fully healthy.
"Hockey did not cause the stroke," Shero told the media. "A return to play will not cause another stroke. He's very comfortable and the doctors are very comfortable.”
The 26-year-old suffered the stroke on January 29, prompting doctors to discover a small hole in his heart. He did not skate for more than four weeks after the stroke and was prescribed blood thinners.
Last season's Norris Trophy finalist signed an eight-year, $58 million contract extension this past summer. He has 10 goals and eight assists in 34 games this season.