"Where our hockey club is right now we have to be open to listening to just about anything and everything, and I am listening," Regier told reporters. "We have to be open to everything, and I think the players recognize that as well.
"You're looking to get a group of top players that are going to play together, not on a one-year basis but going forward on a multiyear basis. That's our focus, and it could involve any players, and I think the players are aware of that."
While the Sabres seem to be building their future around Cody Hodgson, Tyler Ennis and Tyler Myers, the News suggests the likes of Ryan Miller, Thomas Vanek and Jason Pominville could be in play.
However, Miller, who has questioned the team's direction, didn't view Regier's comments at a direct threat.
"It's another one of the mysteries of Darcy," Miller told the News. "I think that's his way of saying we obviously know we have to do something. From his end, he's going to do whatever he feels he needs to do, but it doesn't tell you much. It doesn't tell me much."
Miller, who has a limited no-trade clause, also told the paper a report claiming he submitted a list of eight teams he'd accept a trade to prior to the season is false.
While teams have inquired about Miller, Vanek and Pominville, one league executive told TFP only the latter could realistically be moved this season, if at all.
"To move a player of Miller or Vanek's stature, that's not something that's pieced together over a couple of weeks," the source told TFP. "If anything, these guys are off-season deals. But at the end of the day, you never know what a team is willing to offer."
Regier doesn't appear to be in a rush to trade his top stars, but if the right deal comes along, he'll pull the trigger.
"We're going to try and do some things," Regier said. "The trade deadline, you can feel at times that you're going to get a lot done and you don't get anything done, and vice versa. You can feel like you're not making much headway and you end up doing more things. It's still too early, really, but we'll find out."
With Regehr, Stafford and possibly Pominville on the move before Wednesday's deadline -- Pominville last a limited no-movement clause and might have to approve any deal the Sabres try to make -- Regier could be positioning his club for an interesting summer.
The Sabres have around $14 million in available salary cap space this summer, with just Hodgson, goalie Jhonas Enroth and defenseman Mike Weber their main restricted free agents in need of new deals.
If Regier moves Pominville ($5.3 million cap hit), Vanek ($7.142M) or Miller ($6.25M), things could open up on both the trade front and in the free agent market.
Another source told TFP he believes Vanek won't be back with the Sabres beyond the 2014-15 season, after his contract with the team expires, which could prompt a trade this summer if a deal isn't consummated this week.