Ference, 33, can become an unrestricted free agent at the end of his deal, while Seguin can become a restricted free agent.
Ference has one-year left on his three-year, $6.75 million contract that pays him $2.25 million per season. He'll undoubtedly receive a raise, though the length of an extension is not yet known.
Seguin, 20, is coming towards the end of an entry-level deal. He exploded for 29 goals and 38 assists in 81 games with the Bruins last season.
It's believed Seguin will receive a deal in the six-to-eight year range, worth between $5 million and $7 million per season.
A source close to the situation told TFP on Friday that the Bruins have upped their efforts to sign Seguin after the Carolina Hurricanes signed Jeff Skinner and the Edmonton Oilers locked up Taylor Hall.
Negotiations are ongoing.
Ference and Seguin aren't the only players the Bruins are focused on, though, as one league executive told TFP earlier today that the team has spoken with the representatives for Brad Marchand and Milan Lucic, both of whom have one-year remaining on their current deals and can become RFAs at their conclusion.
It's unclear how close, or far, the Bruins are to signing Marchand and Lucic, though somewhat serious discussions started earlier this month.