The veteran blueliner was able to play the past two games, but the club's medical staff thought it best to keep him out Thursday.
"They stitched it up and everything was good, but a little infection has gotten into it now," Julien said. "He's on antibiotics, and to play it safe, we're going to keep him out (tonight). He's day to day, and it's not long-term."
Seidenberg is expected to be back in the lineup for Saturday's contest against the New York Islanders.
In 76 games with the Bruins this season, Seidenberg has tallied four goals and 18 assists for 22 points, and 39 penalty minutes.
Meanwhile, blueliner Adam McQuaid took a hard check and fell face first into the boards, suffering a cut above the eyebrow on Thursday night, left the game on his own, but did not return to the contest.
Medical staff decided to keep him out for the remainder of the game as he allegedly did not feel right following the hit, while the Bruins hope to have him back in the lineup for Saturday afternoon's matchup against the New York Islanders.